![]() ![]() If you can tell me the equation you are thinking about, then I can help you more. In the Columns tab, below the displayed Bguide2 worksheet, select the Time column header in the Columns box. Units must be added to the time and concentration columns before the dataset can be used to create plots. If you have a model that applies only to single dose and not in the PK libraries, then it is not trivial to use it for multiple dosing unless you can define it through a set of differential equations. Import the file ExamplesWinNonlinSupporting filesBguide2.dat. Note that almost all models in Phoenix are non linear but most are handled through use of differential equations or with built in equations like the 1 compartment model but that handle automatically multiple dosing. I attached a simple example that shows you the steps. You highlight the whole text of this model, create a new model textual and paste the content of the previous model. You then copy that model to the workflow and shift to "edit as textual". The easiest way to deal with this kind of model is to take the Emax model from built in and consider it as your template. I guess you mean using an equation for the response, response that is non linear with respect to the model parameters. ![]()
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